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Anti-VASP Rabbit Monoclonal Antibody

Anti-VASP Rabbit Monoclonal Antibody

ArtNr	BOS-M00303-30ul
Hersteller	Boster
Menge	30ul
Format	Liquid
Applikationen	WB, IP
Clon	BHO-22
Specific against	Human
Host	Rabbit
Isotype	IgG
Alias	Vasodilator-stimulated phosphoprotein;VASP;VASP;
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Manufacturers Product Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturers Research Category	Cytoskeleton/ECM, Extracellular Matrix, Signal Transduction, Structures
Short Description	Boster Bio Anti-VASP Rabbit Monoclonal Antibody catalog # M00303. Tested in WB, IP applications. This antibody reacts with Human.
Description	Boster Bio Anti-VASP Rabbit Monoclonal Antibody catalog # M00303. Tested in WB, IP applications. This antibody reacts with Human.
Gene Name	VASP
Application Details	WB 1:500-1:2000 IP 1:50
Clonality	Monoclonal
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Immunogen	A synthesized peptide derived from human VASP
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Vasodilator-stimulated phosphoprotein
Molecular Weight	39830 MW
Protein Function	Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin- bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation..
Subcellular Localization	Cytoplasm. Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell junction, tight junction. Cell projection, lamellipodium membrane. Cell projection, filopodium membrane. Targeted to stress fibers and focal adhesions through interaction with a number of proteins including MRL family members. Localizes to the plasma membrane in protruding lamellipodia and filopodial tips. Stimulation by thrombin or PMA, also translocates VASP to focal adhesions. Localized along the sides of actin filaments throughout the peripheral cytoplasm under basal conditions. In pre-apoptotic cells, colocalizes with MEFV in large specks (pyroptosomes).
Tissue Specificity	Highly expressed in platelets..

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 30ul

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Lieferung vsl. bis 30.08.2024

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