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Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267

Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267

ArtNr	BOS-M00016-1
Hersteller	Boster
Menge	100ul
Format	Liquid
Applikationen	WB, IHC
Clon	RM267
Specific against	Human
Host	Rabbit
Isotype	IgG
Alias	Cyclin-dependent kinase inhibitor 2A ;Cyclin-dependent kinase 4 inhibitor A;CDK4I;Multiple tumor suppressor 1;MTS-1;p16-INK4a;p16-INK4;p16INK4A;CDKN2A ;CDKN2, MTS1;
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Manufacturers Product Category	Primary Antibodies, Monoclonal Antibodies
Manufacturers Research Category	Cancer, Cancer Susceptibility, Cell Biology, Cell Cycle, Cell Cycle Inhibitors, Epigenetics and Nuclear Signaling, Oncoproteins/Suppressors, p53 Pathway, Transcription, Tumor Suppressors
Short Description	Boster Bio Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267 (Catalog # M00016-1). Tested in IHC, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-p16INK4a (CDKN2A) Rabbit Monoclonal Antibody, Clone#RM267 (Catalog # M00016-1). Tested in IHC, WB applications. This antibody reacts with Human.
Gene Name	CDKN2A
Clonality	Monoclonal
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	50% Glycerol/PBS with 1% BSA and 0.09% sodium azide
Application Details	Immunohistochemistry (IHC): 1:500-1:1000 dilution WB: 1:500-1:1000 dilution.
Immunogen	A peptide corresponding to the C-terminus of human p16INK4a (Cyclin-dependent kinase inhibitor 2A).
Cross-reactivity	This antibody reacts to human p16INK4a (Cyclin-dependent kinase inhibitor 2A).
Purification	Protein A affinity purified from an animal origin-free culture supernatant
Storage	Store at -20°C for one year. Avoid repeated freeze-thaw cycles.
Gene Full Name	Cyclin-dependent kinase inhibitor 2A
Molecular Weight	16533 MW
Protein Function	Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Subcellular Localization	Cytoplasm. Nucleus.
Tissue Specificity	Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific.

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Menge: 100ul

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Lieferung vsl. bis 30.08.2024

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