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Anti-human CD55/Daf Monoclonal Antibody PE Conjugated, Flow Validated

Anti-human CD55/Daf Monoclonal Antibody PE Conjugated, Flow Validated

ArtNr	BOS-FC00910-PE-100tests
Hersteller	Boster
Menge	100 tests
Format	Liquid
Applikationen	FC
Clon	F4-29D9
Specific against	Human
Host	Mouse
Isotype	IgG1 Kappa
Konjugat/Tag	PE
Sensitivity	5ul per sample
Alias	Complement decay-accelerating factor;CD55;CD55;CR, DAF;
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Manufacturers Product Category	Primary Antibodies, Monoclonal Antibodies
Manufacturers Research Category	Cell Type Markers, Immunology
Short Description	Boster Bio Anti-human CD55/Daf Monoclonal Antibody PE Conjugated, Flow Validated (Catalog# FC00910-PE). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Description	Boster Bio Anti-human CD55/Daf Monoclonal Antibody PE Conjugated, Flow Validated (Catalog# FC00910-PE). Tested in Flow Cytometry application(s). This antibody reacts with Human.
Background	Complement decay-accelerating factor, also known as CD55 or DAF, is a protein that, in humans, is encoded by the CD55 gene. This gene encodes a glycoprotein involved in the regulation of the complement cascade. Binding of the encoded protein to complement proteins accelerates their decay, thereby disrupting the cascade and preventing damage to host cells. Antigens present on this protein constitute the Cromer blood group system (CROM). Alternative splicing results in multiple transcript variants. The predominant transcript variant encodes a membrane-bound protein, but alternatively spliced transcripts may produce soluble proteins.
Gene Name	CD55
Clonality	Monoclonal
Concentration	0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	PBS pH 7.2, 0.2% (w/v) BSA, 0.09% (w/v) sodium azide
Application Details	User needs to optimize the dilution ratio for this antibody.
Immunogen	Human umbilical vein endothelial cells (HUVEC)
Purification	Protein A purified
Storage	Store at 2-8°C. Avoid repeated freeze-thaw cycles.
Gene Full Name	Complement decay-accelerating factor
Molecular Weight	41400 MW
Protein Function	This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade..
Subcellular Localization	Isoform 1: Cell membrane; Single-pass type I membrane protein.
Tissue Specificity	Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
Protein Name	Complement decay-accelerating factor

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Menge: 100 tests

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Lieferung vsl. bis 30.08.2024

Express-Lieferung: 7 Tage sparen

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