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Anti-REEP4 Antibody Europäischer Partner

ArtNr BOS-A12670
Hersteller Boster
Menge 0.1mg
Format Liquid
Applikationen WB, ELISA
Specific against Human, Mouse, Rat
Host Rabbit
Isotype IgG
Alias PP432, C8orf20, PP432, Receptor expression-enhancing protein 4
Lieferbar
Manufacturers Product Category
Primary Antibodies
Manufacturers Research Category
Signal Transduction
Short Description
Boster Bio Anti-REEP4 Antibody (Catalog # A12670). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Description
Boster Bio Anti-REEP4 Antibody (Catalog # A12670). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.
Background
Mammalian odorant receptors require accessory proteins such as RTP1 and RTP2 for functional cell surface expression. Receptor expression-enhancing protein (REEP) family members are transmembrane proteins which interact with odorant receptor proteins and may enhance the odorant receptor responses to odorants. Recently studies have shown other chemosensory receptors such as bitter taste receptors are also influenced by RTP and REEP family members. In studies in Xenopus RNAi to reduce REEP4 levels, embryos showed a slightly kinked body axis and were paralyzed. Further analysis revealed downregulated levels of several neural and muscle markers, suggesting the REEP4 may play a role in the maintenance of both the nervous system and musculature.
Gene Name
REEP4
Clonality
Polyclonal
Concentration
1 mg/mL
Contents
REEP4 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Details
REEP4 antibody can be used for detection of REEP4 by Western blot at 1 μg/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. Optimal dilutions for each application should be determined by the researcher.
Immunogen
REEP4 antibody was raised against a 17 amino acid synthetic peptide near the center of human REEP4. The immunogen is located within amino acids 160 - 210 of REEP4.
Purification
REEP4 Antibody is affinity chromatography purified via peptide column.
Storage
REEP4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. Avoid repeated freeze-thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Gene Full Name
Receptor accessory protein 4
Molecular Weight
29395 MW
Protein Function
Microtubule-binding protein required to ensure proper
cell division and nuclear envelope reassembly by sequestering the
endoplasmic reticulum away from chromosomes during mitosis.
Probably acts by clearing the endoplasmic reticulum membrane from
metaphase chromosomes.
Subcellular Localization
Endoplasmic reticulum membrane
Tissue Specificity
Expressed in circumvallate papillae and
testis.
Protein Name
Receptor accessory protein 4

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1mg
Lieferbar: In stock
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