ArtNr |
BOS-A05498-2 |
Hersteller |
Boster
|
Menge |
100 ug/vial |
Format |
Lyophilized |
Applikationen |
WB, IF, ICC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Polyclonal Antibodies |
Short Description |
Boster Bio Anti-NUDT15 Antibody Picoband™ catalog # A05498-2. Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-NUDT15 Antibody Picoband™ catalog # A05498-2. Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. |
Background |
Nudix hydrolase 15 is a protein that in humans is encoded by the NUDT15 gene. This gene encodes an enzyme that belongs to the Nudix hydrolase superfamily. Members of this superfamily catalyze the hydrolysis of nucleoside diphosphates, including substrates like 8-oxo-dGTP, which are a result of oxidative damage, and can induce base mispairing during DNA replication, causing transversions. The encoded enzyme is a negative regulator of thiopurine activation and toxicity. Mutations in this gene result in poor metabolism of thiopurines, and are associated with thiopurine-induced early leukopenia. Multiple pseudogenes of this gene have been identified. |
Gene Name |
NUDT15 |
Application Details |
Western blot, 0.25-0.5 μg/ml, Human Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human ELISA, 0.1-0.5 μg/ml, Human |
Application Notes |
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. |
Clonality |
Polyclonal |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Contents |
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4. |
Immunogen |
E.coli-derived human NUDT15 recombinant protein (Position: C23-L164). Human NUDT15 shares 90.8% amino acid (aa) sequence identity with mouse NUDT15. |
Purification |
Immunogen affinity purified. |
Storage |
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. |
Reconstitution |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Molecular Weight |
19 kDa |
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