ArtNr |
BOS-A03754 |
Hersteller |
Boster
|
Menge |
100ul |
Format |
Liquid |
Applikationen |
WB |
Clon |
2F1 |
Specific against |
Human |
Host |
Mouse |
Alias |
Nucleosome-remodeling factor subunit BPTF;Bromodomain and PHD finger-containing transcription factor;Fetal Alz-50 clone 1 protein;Fetal Alzheimer antigen;BPTF;FAC1, FALZ; |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies, Monoclonal Antibodies |
Short Description |
Boster Bio Anti-BPTF/Falz Monoclonal Antibody catalog # A03754. Tested in WB applications. This antibody reacts with Human. |
Description |
Boster Bio Anti-BPTF/Falz Monoclonal Antibody catalog # A03754. Tested in WB applications. This antibody reacts with Human. |
Gene Name |
BPTF |
Clonality |
Monoclonal |
Contents |
Ascitic fluid containing 0.03% sodium azide. |
Application Details |
WB, 1:500-1:2000 |
Immunogen |
Purified recombinant fragment of human BPTF expressed in E. Coli. |
Purification |
Ascitic fluid |
Storage |
Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Gene Full Name |
Nucleosome-remodeling factor subunit BPTF |
Molecular Weight |
338262 MW |
Protein Function |
Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors. |
Subcellular Localization |
Cytoplasm. Nucleus. In brains of Alzheimer disease patients, present in a subset of amyloid- containing plaques. |
Tissue Specificity |
Ubiquitously expressed, with highest levels in testis. Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex (at protein level).. |
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