ArtNr |
BOS-A00993-5-10ug |
Hersteller |
Boster
|
Menge |
10ug |
Format |
Lyophilized |
Applikationen |
WB, FC, ELISA |
Specific against |
Mouse, Rat |
Host |
Rabbit |
Lieferbar |
|
Manufacturers Product Category |
Primary Antibodies, Rabbit Polyclonal Antibodies |
Short Description |
Boster Bio Anti-UPAR/Plaur Antibody Picoband™ catalog # A03740-1. Tested in WB, FCM(Intracellular), ELISA applications. This antibody reacts with Mouse, Rat. |
Description |
Boster Bio Anti-UPAR/Plaur Antibody Picoband™ catalog # A03740-1. Tested in WB, FCM(Intracellular), ELISA applications. This antibody reacts with Mouse, Rat. |
Background |
This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined. |
Gene Name |
PLAUR |
Application Details |
Western blot, 0.25-0.5 μg/ml, Mouse, Rat Flow Cytometry (Intracellular), 1-3 μg/1x106 cells, Rat ELISA, 0.1-0.5 μg/ml, Rat |
Application Notes |
Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. |
Clonality |
Polyclonal |
Concentration |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Contents |
Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4. |
Immunogen |
E.coli-derived rat UPAR/Plaur recombinant protein (Position: L25-R261). Rat Plaur shares 63.7% and 90.3% amino acid (aa) sequence identity with human and mouse Plaur, respectively. |
Purification |
Immunogen affinity purified. |
Storage |
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. |
Reconstitution |
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml. |
Molecular Weight |
50 kDa |
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