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PI3KCG Antibody (Center) Blocking Peptide

ArtNr ABC-BP8180c
Hersteller Abcepta
Menge 500 ug
Kategorie
Typ Peptides
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products PIK3CG, Phosphatidylinositol 4, 5-bisphosphate 3-kinase catalytic subunit gamma isoform, 5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma, Phosphoinositide-3-kinase catalytic gamma polypeptide, PI3Kgamma, PI3-kinase subunit gamma, PI3K-gamma, PtdIns-3-kinase subunit gamma, PtdIns-3-kinase subunit p110-gamma, p110gamma, Serine/threonine protein kinase PIK3CG, p120-PI3K
Lieferbar
Primary Accession
P48736
Bio Background
PI3KCG belongs to the pi3/pi4-kinase family of proteins. It is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene for this protein is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias.
Bio References
Andreozzi, F., et al., Endocrinology 145(6):2845-2857 (2004).Reddy, S.A., et al., Biochem. Biophys. Res. Commun. 316(4):1022-1028 (2004).Osaki, M., et al., J. Cancer Res. Clin. Oncol. 130(1):8-14 (2004).Khan, N.A., et al., J. Neurovirol. 9(6):584-593 (2003).Theberge, J.F., et al., Arch. Biochem. Biophys. 420(1):9-17 (2003).
Gene ID
5294
Gene Name
PIK3CG
Subtitle
Synthetic peptide
Target/Specificity
The synthetic peptide sequence used to generate the antibody AP8180c was selected from the Center region of human PI3KCG. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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