ArtNr |
ABC-BP8037a |
Hersteller |
Abcepta
|
Menge |
500 ug |
Kategorie |
|
Typ |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
PIP5K1A, Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha, 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha, Phosphatidylinositol 4-phosphate 5-kinase type I alpha, PIP5K1-alpha, PIP5KIalpha, PtdIns(4)P-5-kinase 1 alpha |
Lieferbar |
|
Primary Accession |
Q99755 |
Bio Background |
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. |
Bio References |
Doughman, R.L., et al., J. Biol. Chem. 278(25):23036-23045 (2003).Loijens, J.C., et al., J. Biol. Chem. 271(51):32937-32943 (1996).Xie, Y., et al., Cytogenet. Cell Genet. 88 (3-4), 197-199 (2000). |
Gene ID |
8394 |
Gene Name |
|
Subtitle |
Synthetic peptide |
Target/Specificity |
The synthetic peptide sequence used to generate the antibody AP8037a was selected from the N-term region of human PIP5K1A . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
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