ArtNr |
ABC-BP7770a |
Hersteller |
Abcepta
|
Menge |
500 ug |
Kategorie |
|
Typ |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
FLNA, Alpha-filamin, Filamin-1, Endothelial actin-binding protein, Actin-binding protein 280, ABP-280, Non-muscle filamin, FLN, FLN1, Filamin-A, FLN-A |
Lieferbar |
|
Primary Accession |
P21333 |
Bio Background |
Actin-binding protein 280, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers. |
Bio References |
Ravid, D., Exp. Cell Res. 314 (15), 2762-2773 (2008)Maceyka, M., Mol. Cell. Biol. 28 (18), 5687-5697 (2008) |
Gene ID |
2316 |
Gene Name |
FLNA |
Subtitle |
Synthetic peptide |
Target/Specificity |
The synthetic peptide sequence used to generate the antibody AP7770a was selected from the Y1046 region of human FLNA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
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