Similar products |
PCSK2, PC2, NEC2, KEX2-like endoprotease 2, NEC 2, Neuroendocrine convertase 2, Prohormone convertase 2, Proprotein convertase 2 |
Bio Background |
PCSK2 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This protein is a proinsulin-processing enzyme that plays a key role in regulating insulin biosynthesis. The protein is also known to cleave proopiomelanocortin, proenkephalin, prodynorphin and proluteinizing-hormone-releasing hormone. |
Bio References |
Leak, T.S., Keene, K.L. Mol. Genet. Metab. 92 (1-2), 145-150 (2007)Shen, X., Li, Q.L. Am. J. Physiol. Endocrinol. Metab. 288 (1), E236-E245 (2005)Tzimas, G.N., Chevet, E. BMC Cancer 5, 149 (2005)Seidah, N.G., Mattei, M.G. Genomics 11 (1), 103-107 (1991) |