Bio Background |
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. In prostate cancer, KLK15 has increased expression, which indicates its possible use as a diagnostic or prognostic marker for prostate cancer. |
Bio References |
Yousef, G.M., et al., J. Clin. Oncol. 21(16):3119-3126 (2003).Yousef, G.M., et al., Br. J. Cancer 87(11):1294-1300 (2002).Diamandis, E.P., et al., Expert Rev Mol Diagn 1(2):182-190 (2001).Takayama, T.K., et al., Biochemistry 40(6):1679-1687 (2001).Yousef, G.M., et al., J. Biol. Chem. 276(1):53-61 (2001). |