ArtNr |
ABC-BP3711a |
Hersteller |
Abcepta
|
Menge |
500 ug |
Kategorie |
|
Typ |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
PDGFRB, PDGFR, PDGFR1, Platelet-derived growth factor receptor beta, Beta platelet-derived growth factor receptor, Beta-type platelet-derived growth factor receptor, CD140 antigen-like family member B, Platelet-derived growth factor receptor 1, PDGF-R-beta, CD140b, PDGFR-beta, PDGFR-1 |
Lieferbar |
|
Primary Accession |
P09619 |
Bio Background |
This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia. |
Bio References |
Huang, D., et al. Cancer Res. 70(3):1053-1062(2010)Wetterskog, D., et al. Mol. Cancer Res. 7(12):2031-2039(2009)Guo, X., et al. J. Biol. Chem. 284(43):29376-29382(2009)Koos, B., et al. Am. J. Pathol. 175(4):1631-1637(2009) |
Gene ID |
5159 |
Gene Name |
PDGFRB |
Subtitle |
Synthetic peptide |
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