ArtNr |
ABC-BP2784c |
Hersteller |
Abcepta
|
Menge |
500 ug |
Kategorie |
|
Typ |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
FKBP3, Rotamase, FKBP25, FKBP-25, Peptidyl-prolyl cis-trans isomerase FKBP3, 25 kDa FK506-binding protein, 25 kDa FKBP, FKBP-3, Immunophilin FKBP25, FK506-binding protein 3, PPIase FKBP3, Rapamycin-selective 25 kDa immunophilin |
Lieferbar |
|
Primary Accession |
Q00688 |
Bio Background |
FKBP3 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. |
Bio References |
Yang, W.M., EMBO J. 20 (17), 4814-4825 (2001)Jin, Y.J., Proc. Natl. Acad. Sci. U.S.A. 90 (16), 7769-7773 (1993) |
Gene ID |
2287 |
Gene Name |
FKBP3 |
Subtitle |
Synthetic peptide |
Target/Specificity |
The synthetic peptide sequence used to generate the antibody AP2784c was selected from the Center region of human FKBP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
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