ArtNr |
ABC-BP21701c |
Hersteller |
Abcepta
|
Menge |
500 ug |
Kategorie |
|
Typ |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
CACNL1A4, L type, BI, Brain calcium channel I, Calcium channel, Voltage-dependent P/Q-type calcium channel subunit alpha-1A, CACNA1A, alpha-1 polypeptide isoform 4, Voltage-gated calcium channel subunit alpha Cav21, CACH4, CACN3 |
Lieferbar |
|
Primary Accession |
O00555 |
Bio Background |
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by the funnel toxin (Ftx) and by the omega-agatoxin- IVA (omega-Aga-IVA). They are however insensitive to dihydropyridines (DHP), and omega-conotoxin-GVIA (omega-CTx-GVIA). |
Bio References |
Hans M., et al.Biophys. J. 76:1384-1400(1999).Ophoff R.A., et al.Cell 87:543-552(1996).Zhuchenko O., et al.Nat. Genet. 15:62-69(1997).Toru S., et al.J. Biol. Chem. 275:10893-10898(2000).Grimwood J., et al.Nature 428:529-535(2004). |
Gene ID |
773 |
Gene Name |
|
Subtitle |
Synthetic peptide |
Target/Specificity |
The synthetic peptide sequence is selected from aa 918-932 of HUMAN CACNA1A |
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