ArtNr |
ABC-BP2022a |
Hersteller |
Abcepta
|
Menge |
500 ug |
Kategorie |
|
Typ |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
Neurogenin-1, NEUROG1, NGN, BHLHA6, NEUROD3, NGN1, Class A basic helix-loop-helix protein 6, Neurogenic basic-helix-loop-helix protein, Neurogenic differentiation factor 3, NeuroD3, bHLHa6, NGN-1 |
Lieferbar |
|
Primary Accession |
Q92886 |
Bio Background |
Basic helix-loop-helix (bHLH) proteins are transcription factors involved in determining cell type during development. NeuroG1 is a bHLH protein with dual cell-fate specification roles. It functions during neurogenesis, and it has also been shown to inhibit the differentiation of neural stem cells into astrocytes. NeuroG1 promotes neurogenesis by functioning as a transcriptional activator, yet it inhibits astrocyte differentiation by compartmentalizing the CREB-binding protein transcription complex away from astrocyte differentiation genes and by inhibiting STAT transcription factors essential for gliogenesis. |
Bio References |
Tamimi, R.M., et al., Genomics 40(2):355-357 (1997).McCormick, M.B., et al., Mol. Cell. Biol. 16(10):5792-5800 (1996). |
Gene ID |
4762 |
Gene Name |
NEUROG1 |
Subtitle |
Synthetic peptide |
Other Accession |
NP_006152 |
Target/Specificity |
The synthetic peptide sequence used to generate the antibody AP2022a was selected from the N-term region of human NeuroG1 . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
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