ArtNr |
ABC-BP19964c |
Hersteller |
Abcepta
|
Menge |
500 ug |
Kategorie |
|
Typ |
Peptides |
Format |
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Similar products |
YB1, NSEP1, YBX1, Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Y-box transcription factor, Y-box-binding protein 1, YB-1, CBF-A, DBPB, EFI-A |
Lieferbar |
|
Primary Accession |
P67809 |
Bio Background |
Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes. Regulates the transcription of numerous genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. |
Bio References |
Yu, Y.N., et al. Int. J. Oncol. 37(2):483-492(2010)Lovett, D.H., et al. Biochem. Biophys. Res. Commun. 398(3):482-488(2010)Takahashi, M., et al. Cancer Sci. 101(6):1367-1373(2010)Cobbold, L.C., et al. Oncogene 29(19):2884-2891(2010)To, K., et al. Cancer Res. 70(7):2840-2851(2010) |
Gene ID |
4904 |
Gene Name |
|
Subtitle |
Synthetic peptide |
Other Accession |
P62961; Q28618; P62960; P67808; NP_004550.2 |
Target/Specificity |
The synthetic peptide sequence is selected from aa 164-178 of HUMAN YBX1 |
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