Bio Background |
NMYC interactor (NMI) encodes a protein that interactswith NMYC and CMYC (two members of the oncogene Myc family), andother transcription factors containing a Zip, HLH, or HLH-Zipmotif. The NMI protein also interacts with all STATs except STAT2and augments STAT-mediated transcription in response to cytokinesIL2 and IFN-gamma. The NMI mRNA has low expression levels in allhuman fetal and adult tissues tested except brain and has highexpression in cancer cell line-myeloid leukemias. [provided byRefSeq]. |
Bio References |
Davila, S., et al. Genes Immun. 11(3):232-238(2010)Fillmore, R.A., et al. Int. J. Cancer 125(3):556-564(2009)Quaye, L., et al. Br. J. Cancer 100(6):993-1001(2009)Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)Quaye, L., et al. Clin. Cancer Res. 14(18):5833-5839(2008) |