Bio Background |
Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha-8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins (By similarity). |
Bio References |
Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010)Hancock, D.B., et al. Nat. Genet. 42(1):45-52(2010)Kahai, S., et al. PLoS ONE 4 (10), E7535 (2009) :Huang, J.T., et al. Int. J. Mol. Med. 15(4):719-724(2005)Brandenberger, R., et al. J. Cell Biol. 154(2):447-458(2001) |