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TSC22D3, DSIPI, GILZ, TSC22 domain family protein 3, DSIP-immunoreactive peptide, Delta sleep-inducing peptide immunoreactor, Glucocorticoid-induced leucine zipper protein, TSC-22-like protein, TSC-22-related protein, TSC-22R, hDIP, Protein DIP |
Bio Background |
The protein encoded by this gene shares significantsequence identity with the murine TSC-22 and Drosophila shs, bothof which are leucine zipper proteins, that function astranscriptional regulators. The expression of this gene isstimulated by glucocorticoids and interleukin 10, and it appears toplay a key role in the anti-inflammatory and immunosuppressiveeffects of this steroid and chemokine. Transcript variants encodingdifferent isoforms have been identified for this gene. [provided byRefSeq]. |
Bio References |
Latre de Late, P., et al. J. Biol. Chem. 285(8):5594-5605(2010)Lekva, T., et al. J. Clin. Endocrinol. Metab. 95(1):246-255(2010)Soundararajan, R., et al. Proc. Natl. Acad. Sci. U.S.A. 106(19):7804-7809(2009)Zhang, X.H., et al. Clin. Exp. Allergy 39(5):647-654(2009)Redjimi, N., et al. Mol. Cancer 8, 83 (2009) : |