Bio Background |
This gene encodes a protein that is upregulated inresponse to various cytokines. The encoded protein may play a rolein cell cycle progression. A translocation between this gene andthe myeloid/lymphoid leukemia gene, resulting in expression of achimeric protein, has been associated with acute myelomonocyticleukemia. Pseudogenes exist on chromosomes 7 and 8. Alternativelyspliced transcript variants have been described. [provided byRefSeq]. |
Bio References |
Sugiura, T., et al. Exp. Cell Res. 313(4):782-790(2007)Leaw, C.L., et al. Cell. Mol. Life Sci. 61(17):2264-2273(2004)Hashii, Y., et al. Leukemia 18(9):1546-1548(2004)Fukuda, S., et al. Biochem. Biophys. Res. Commun. 292(3):593-600(2002)Choong, M.L., et al. FEBS Lett. 496 (2-3), 109-116 (2001) : |