Bio Background |
ADP-ribosylation is a reversible posttranslationalmodification used to regulate protein function.ADP-ribosyltransferases, such as ART3, transfer ADP-ribose fromNAD+ to the target protein, and ADP-ribosylhydrolases (see PARG; MIM 603501) reverse the reaction (Glowacki et al., 2002 [PubMed12070318]). |
Bio References |
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Davila, S., et al. Genes Immun. 11(3):232-238(2010)Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)Okada, H., et al. PLoS Genet. 4 (2), E26 (2008) : |