KRT6B Antibody (Center) Blocking peptide

The protein encoded by this gene is a member of thekeratin gene family. The type II cytokeratins consist of basic orneutral proteins which are arranged in pairs of heterotypic keratinchains coexpressed during differentiation of simple and stratifiedepithelial tissues. As many as six of this type II cytokeratin(KRT6) have been identified; the multiplicity of the genes isattributed to successive gene duplication events. The genes areexpressed with family members KRT16 and/or KRT17 in the filiformpapillae of the tongue, the stratified epithelial lining of oralmucosa and esophagus, the outer root sheath of hair follicles, andthe glandular epithelia. Mutations in these genes have beenassociated with pachyonychia congenita. The type II cytokeratinsare clustered in a region of chromosome 12q12-q13. [provided byRefSeq].

3854

Synthetic peptide