HIST1H2AB Antibody (N-term) Blocking peptide

Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. This structure consists of approximately 146 bp of DNAwrapped around a nucleosome, an octamer composed of pairs of eachof the four core histones (H2A, H2B, H3, and H4). The chromatinfiber is further compacted through the interaction of a linkerhistone, H1, with the DNA between the nucleosomes to form higherorder chromatin structures. This gene is intronless and encodes amember of the histone H2A family. Transcripts from this gene lackpolyA tails; instead, they contain a palindromic terminationelement. This gene is found in the large histone gene cluster onchromosome 6p22-p21.3.

3012; 8335

Synthetic peptide