Bio Background |
This gene produces alternative transcripts encoding twodistinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specializedsynapses known as synaptic ribbons. Both proteins contain a NAD+binding domain similar to NAD+-dependent 2-hydroxyaciddehydrogenases. A portion of the 3' untranslated region was used tomap this gene to chromosome 21q21.3; however, it was noted thatsimilar loci elsewhere in the genome are likely. Blast analysisshows that this gene is present on chromosome 10. [provided byRefSeq]. |
Bio References |
Bao, B.Y., et al. Clin. Chim. Acta 411 (17-18), 1232-1237 (2010) :Liu, H., et al. Prostate (2010) In press :Kim, S.T., et al. Prostate (2010) In press :Gallagher, D.J., et al. Clin. Cancer Res. 16(10):2819-2832(2010)Kitamura, F., et al. Int. Arch. Allergy Immunol. 152 SUPPL 1, 18-21 (2010) : |