[Novoprotein] Recombinant Human Lymphocyte Antigen 64/LY64/CX180/RP105 (C-Fc)

CD180, also known as RP105, is a type I transmembrane glycoprotein with extracellular leucine-rich repeats (LRR) typically found in Toll-like receptor (TLR) family members. There are more than 320 CD unique clusters & subclusters have been identified. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. The cell surface receptor complex RP105/MD1 which is formed by RP105 interact with a MD1 extracellular molecule, & then the complex lead to proliferation & up-regulation of a costimulatory molecule B7.2/CD86 by inducing B-cell activation in humans & mice. RP105 also plays a role in LPS response because B cells lacking RP105 show hyporesponsiveness to LPS.

Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

94.4kD

Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.