Tyrosine-Protein Phosphatase Non-Receptor Type 1/PTPN1

Tyrosine-Protein Phosphatase Non-Receptor Type 1 (PTPN1) is an enzyme containing 1 tyrosine-protein phosphatase domain. PTPN1 belongs to the protein tyrosine phosphatase (PTP) family, member of which catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. PTPs were isolated & identified based on their enzymatic activity & amino acid sequence. PTPN1 can dephosphorylate the phosphotyrosine residues of the activated insulin receptor kinase. It acts as a regulator of endoplasmic reticulum unfolded protein response & regulates the EFNA5-EPHA3 signaling pathway. PTPN1 is implicated in the regulation of cell growth, differentiation, cell responses to cytokines & hormones, & malignancy transformation.

P18031

Store at < -20C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Dry Ice/Polar Packs