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[Novoprotein] Recombinant Human CXC73/Parafibromin/HRPT2 (N-6His)

ArtNr CE45-500ug
Hersteller Bon Opus
Menge 500ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Human
Host E.coli
Konjugat/Tag His
Purity Greater than 95% as determined by reducing SDS-PAGE.
Sequence MGSSHHHHHHSSGLVPRGSHMADVLSVLRQYNIQK KEIVVKGDEVIFGEFSWPKNVKTNYVVWGTGKEGQ PREYYTLDSILFLLNNVHLSHPVYVRRAATENIPV VRRPDRKDLLGYLNGEASTSASIDRSAPLEIGLQR STQVKRAADEVLAEAKKPRIEDEECVRLDKERLAA RLEGHKEGIVQTEQIRSLSEAMSVEKIAAIKAKIM AKKRSTIKTDLDDDITALKQRSFVDAEVDVTRDIV SRE
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Parafibromin, Cell Division Cycle Protein 73 Homolog, Hyperparathyroidism 2 Protein, CDC73, C1orf28, HRPT2
Similar products CDC73
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Background
Parafibromin is expressed in the adrenal & parathyroid glands, kidney, & heart. As a tumor supressor, Parafibromin may be involved in transcriptional & post-transcriptional control pathways, also through the regulation of cyclin D1/PRAD1 expression, involved the cell cycle progression. Parafibromin is a component of the the PAF protein complex & interacts with a Set1-like complex that has histone methyltransferase activity & methylates histone H3. Defects in Parafibromin can cause hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, & parathyroid carcinoma.
Description
Recombinant Human CDC73 is produced by our E.coli expression system & the target gene encoding Met1-Glu260 is expressed with a 6His tag at the N-terminus.
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Formulation
Lyophilized from a 0.2 um filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Molecular Weight
32, 77
Reconstitution
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Seq Length
Met1-Glu260
Ship Description
The product is shipped at ambient temperature.
Storage
Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500ug
Lieferbar: In stock
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