[Novoprotein] Recombinant Human Transforming Growth Factor a/TGFa

Transforming Growth Factor alpha (TGF-alpha) belongs to the EGF family of cytokines. It is a mitogenic polypeptide & secreted protein, which is expressed by monocytes, keratinocytes, & various tumor cells. TGFalpha contains two chains, protransforming growth factor alpha & transforming growth factor alpha. It can bind to the EGF receptor that synergistically with TGFbeta to stimulate anchorage-independent cell proliferation & produce a mitogenic response. TGFalpha interacts with the PDZ domains of MAGI3, SDCBP & SNTA1. The interaction with SDCBP is required for the targeting to the cell surface.

Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.

5, 55

Val41-Val90

Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.