ArtNr |
NKM-LAR3001-0.5mg |
Hersteller |
NKMAX
|
Menge |
0.5mg |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Konjugat/Tag |
Non-Tagged |
Purity |
> 95% by SDS - PAGE |
Sequence |
MQEEDLPRPS ISAEPGTVIP LGSHVTFVCR GPVGVQTFRL ERESRSTYND TEDVSQASPS ESEARFRIDS VSEGNAGPYR CIYYKPPKWS EQSDYLELLV KETSG |
NCBI |
NP_002278 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Leukocyte-associated immunoglobulin-like receptor 1 isoform a, Lair1, LAIR-1 (Extracellular domain), LAIR-1, mLAIR1, CD305 antigen, Leukocyte-associated immunoglobulin-like receptor 1, Leukocyte-associated immunoglobulin-like receptor 1 isoform a 5133400O11Rik, CD305, D7Bwg0421e, LAIR 1, LAIR1 protein, Leukocyte associated Ig like receptor 1, Leukocyte associated immunoglobulin like receptor 1, |
Lieferbar |
|
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
1 mg/ml (determined by Bradford assay) |
Description |
LAIR-1 is a glycoprotein (ca.32kDa) expressed on the surface of the majority of human peripheral blood mononuclear leukocytes including T cells, B cells, NK cells, macrophages and dendritic cells. LAIR-1 functions as an inhibitory receptor in NK cells, T cells and B cells. Lair-1 consists of a leader sequence, extracellular domain, transmembrane domain, cytoplasmic region. The extracellular domain of LAIR-1 ( 22-125aa) was overexpressed in E. coli, and purified by using conventional chromatography techniques. |
Domain |
22-125aa |
Expression System |
E.coli |
Formulation |
Liquid. In 20 mM Tris-HCl (pH7.5) 50mM NaCl, 1mM EDTA |
Gene Category |
Immunology |
General References |
Sathish JG., et al. (2001) J Immunol. 166(3):1763-70. Meyaard L., et al. (1999) J. Immunol. 162, 5800-4. |
Molecular Weight |
11.7 kDa (105 aa), confirmed by MALDI-TOF. |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
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