ArtNr |
NKM-CKS0801-0.5mg |
Hersteller |
NKMAX
|
Menge |
0.5mg |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Konjugat/Tag |
T7-Tag |
Purity |
> 95% by SDS - PAGE |
Sequence |
MASMTGGQQM GRGSHMAHKQ IYYSDKYFDE HYEYRHVMLP RELSKQVPKT HLMSEEEWRR LGVQQSLGWV HYMIHEPEPH ILLFRRPLPK DQQK |
NCBI |
NP_001818 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Cyclin-dependent kinases regulatory subunit 2, CKSHS2, CDC28 Protein kinase 2, Cyclin-dependent kinases regulatory subunit 2, CKS2, Cyclin-dependent kinases regulatory subunit 2 CDC28 protein kinase regulatory subunit 2, CKS 2, CKS1(S, cerevisiae Cdc28/Cdc2 kinase subunit) homolog 2, Cyclin dependent kinases regulatory subunit 2. |
Lieferbar |
|
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
1 mg/ml (determined by Bradford assay) |
Description |
CKS2, also known as CDC28 Protein kinase 2 associates with the catalytic subunit of cyclin-dependent kinases and has therefore been assumed to play a direct role in cell cycle regulation. The function of CKS2 in somatic mammalian cells is not well understood although it is required for the first metaphase/anaphase transition during the meiosis. Emerging evidence shows that elevated expression of CKS2 protects the cells from apoptosis. Recombinant CKS2 fused with T7-tag was expressed in E. coli and purified by conventional chromatography techniques. |
Domain |
1-79aa |
Expression System |
E.coli |
Formulation |
Liquid in 20mM Tris pH7.5, 20% Glycerol |
Gene Category |
Cell Cycle |
General References |
Martinsson-Ahlzen HS., et al: (2008) Mol Cell Biol. 28(18):5698-709. Lan Y., et al: (2008) Int J Cancer. 123(3):543-51. |
Molecular Weight |
11.3kDa (94aa), confirmed by MALDI-TOF. |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
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