ArtNr |
NKM-ATGP3664-250ug |
Hersteller |
NKMAX
|
Menge |
250ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Konjugat/Tag |
hIgG-His-Tag |
Purity |
> 95% by SDS - PAGE |
Sequence |
MVPPPENVRM NSVNFKNILQ WESPAFAKGN LTFTAQYLSY RIFQDKCMNT TLTECDFSSL SKYGDHTLRV RAEFADEHSD WVNITFCPVD DTIIGPPGMQ VEVLADSLHM RFLAPKIENE YETWTMKNVY NSWTYNVQYW KNGTDEKFQI TPQYDFEVLR NLEPWTTYCV QVRGFLPDRN KAGEWSEPVC EQTTHDETVP SLEPKSCDKT HTCPPCPAPE LLGGPSVFLF PP |
NCBI |
NP_000619 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Interleukin-10 receptor subunit beta, IL10RB, CDW210B, CRF2-4, CRFB4, D21S58, D21S66, IL-10R2 |
Lieferbar |
|
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
1.0mg/ml (determined by Absorbance at 280nm) |
Description |
IL10RB, also known as interleukin-10 receptor subunit beta, is a transmembrane glycoprotein that functions as a co-receptor for several class 2 cytokines including Interleukins-10, -22, -26, -28A/IFN-lambda 2, -28B/IFN-lambda 3, and -29/IFN-lambda. Co-expression of this and IL10RA proteins has been shown to be required for IL10-induced signal transduction. Recombinant human IL10RB protein, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Domain |
20-220aa |
Endotoxin |
< 1.0 EU per 1ug of protein (determined by LAL method) |
Expression System |
Baculovirus |
Formulation |
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Gene Category |
Immunology |
General References |
Khare V., et al, (2015) Cancer Immunol Res. 3:1227-1235. Spencer SD., et al, (1998) J. Exp. Med. 187: 571-578. |
Molecular Weight |
50.5kDa (440aa) 50-70KDa (SDS-PAGE under reducing conditions.) |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
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