Hersteller |
NKMAX
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Menge |
250ug |
ArtNr |
NKM-ATGP3640-250ug |
Targets |
CD213a2;;IL13 |
Konjugat/Tag |
hIgG-His-Tag |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Alias |
Interleukin-13 receptor subunit alpha-2, IL13RA2, CD213A2, CT19, IL-13R, IL13BP |
Purity |
> 85% by SDS - PAGE |
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
0.5mg/ml (determined by Absorbance at 280nm) |
Description |
IL13RA2, also known as interleukin-13 receptor subunit alpha-2, is a membrane bound protein that in humans is encoded by the IL13RA2 gene. It is able to regulate the effects of both IL13 and IL14, despite the fact it is unable to bind directly to the latter. Also, this protein plays an important role in the Th2-polarized immune responses characteristic of a variety of pathologies, including parasitic infection and allergic asthma. Recombinant human IL13RA2, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Domain |
27-343aa |
Endotoxin |
< 1.0 EU per 1ug of protein (determined by LAL method) |
Expression System |
Baculovirus |
Formulation |
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol. |
Gene Category |
Immunology, Hormones & Cytokines |
General References |
Caput D., et al, (1996) J. Biol. Chem. 271:16921-16926. Donaldson DD., et al, (1998) J. Immunol. 161:2317-2324. |
Molecular Weight |
64.3kDa (559aa) 70-100kDa (SDS-PAGE under reducing conditions.) |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
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