Recombinant human TPST2 protein

SDS-PAGE

TPST2, also known as protein-tyrosine sulfotransferase 2, is the enzyme that catalyzes the sulfation reaction of protein tyrosines, a post-translational modification of proteins. This protein is a type II integral membrane protein found in the Golgi body. Compared to TPST1, TPST2 has similar tissue distribution and overlapping substrate specificity. In contrast to TPST1-/- males with normal fertility in mice, TPST2-/- males are infertile due to severe defects in sperm motility. Recombinant human TPST2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

< 1.0 EU per 1ug of protein (determined by LAL method)

Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol.

Danan LM., et al. (2008). J Am Soc Mass Spectrom. 19(10):1459-1466.
Kehoe J.W. and Bertozzi C.R. (2000) Chemistry & Biology. 7:57-61.

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.