ArtNr |
NKM-ATGP1087-100ug |
Hersteller |
NKMAX
|
Menge |
100ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Konjugat/Tag |
His-Tag |
Purity |
> 90% by SDS - PAGE |
Sequence |
MGSSHHHHHH SSGLVPRGSH MSDRKAVIKN ADMSEDMQQD AVDCATQAME KYNIEKDIAA YIKKEFDKKY NPTWHCIVGR NFGSYVTHET KHFIYFYLGQ VAILLFKSG |
NCBI |
NP_542408 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Dynein light chain 2 LC8-type 2, Dynein light chain 2, LC8-type 2, Dlc2, DNCL1B, DLC8b |
Lieferbar |
|
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
1 mg/ml (determined by Bradford assay) |
Description |
Dynein light chain 2, cytoplasmic, also known DYNLL2, is a large protein complex composed of six distinct subunits and is responsible for most intracellular movement toward the minus ends of microtubules. Dyneins are multisubunit, high molecular weight ATPases that interact with microtubules to generate force by converting the chemical energy of ATP into the mechanical energy of movement. DYNLL2 is a highly conserved eukaryotic hub protein with dozens of binding partners and various functions beyond being a subunit of dynein and myosin Va motor proteins. Recombinant human DYNLL2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. |
Domain |
1-89aa |
Expression System |
E.coli |
Formulation |
Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 30% glycerol, 0.2M NaCl |
Gene Category |
Cytoskeleton |
General References |
Radnai L., et al. (2010) J Biol chem. 285(49):38649-57. Lu J., et al. (2005) Biochem Biophys Res Commun. 331(1):153-8. |
Molecular Weight |
12.5 kDa (109aa), confirmed by MALDI-TOF |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
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