ArtNr |
NKM-ATGP0933-0.5mg |
Hersteller |
NKMAX
|
Menge |
0.5mg |
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Konjugat/Tag |
His-Tag |
Purity |
> 90% by SDS - PAGE |
Sequence |
MGSSHHHHHH SSGLVPRGSH MAEGSPGTPD ESTPPPRKKK KDIRDYNDAD MARLLEQWEK DDDIEEGDLP EHKRPSAPVD FSKIDPSKPE SILKMTKKGK TLMMFVTVSG SPTEKETEEI TSLWQGSLFN ANYDVQRFIV GSDRAIFMLR DGSYAWEIKD FLVGQDRCAD VTLEGQVYPG KGGGSKEKNK TKQDKGKKKK EGDLKSRSSK EENRAGNKRE DL |
NCBI |
NP_055969 |
ECLASS 5.1 |
34160400 |
ECLASS 6.1 |
34160400 |
ECLASS 8.0 |
42020190 |
ECLASS 9.0 |
42020190 |
ECLASS 10.0.1 |
32160409 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
LDLR chaperone MESD, BOCA, KIAA0081, MESD |
Lieferbar |
|
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
1.0 mg/ml (determined by BCA assay) |
Description |
MESDC2, also known as Mesoderm development candidate 2, is required for formation of the primitive streak and mesoderm during embryogenesis. This protein binds to the Wnt co-receptors LRP5 and LRP6 in the endoplasmic reticulum and is required for their proper folding and cell surface expression. Recombinant human MESDC2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
Domain |
34-234aa |
Expression System |
E.coli |
Formulation |
Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol 0.1M NaCl, 1mM DTT |
Gene Category |
Heat Shock Proteins |
General References |
Kohler C, et al. (2006). J Struct Funct Genomics, 7:131-8. Wines ME., et al. (2001). Genomics., 72:88-98. |
Molecular Weight |
24.9 kDa (222aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher) |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
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