Hersteller |
NKMAX
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Menge |
0.5mg |
ArtNr |
NKM-ATGP0670-0.5mg |
Konjugat/Tag |
His-Tag |
eClass 6.1 |
34160400 |
eClass 9.0 |
42020190 |
Lieferbar |
|
Alias |
Prolyl 4-hydroxylase subunit beta, P4Hbeta, PDI, PDIA1, PHD, PO4DB, PO4HB, ERBA2L, Prolyl 4-hydroxylase subunit beta |
Purity |
> 90% by SDS - PAGE |
Antigen Species |
Human |
Applications info |
SDS-PAGE |
Concentration |
1 mg/ml (determined by Bradford assay) |
Description |
P4HB, prolyl 4 hydroxylase subunit beta, is a multifunctional and highly abundant enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This protein is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Recombinant human P4HB protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
Domain |
18-508aa |
Expression System |
E.coli |
Formulation |
Liquid. In 20 mM Tris-HCl (pH 8.0) containing 10% Glycerol |
Gene Category |
Heat Shock Proteins |
General References |
Pfander D., et al. (2006) Am J Pathol. 169(2):491-502. Kivirikko KI., (1991) J Hepatol. 13 Suppl 3:S2-7. |
Molecular Weight |
57.5 kDa(512aa), confirmed by MALDI-TOF |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
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