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Recombinant human NQO-1 protein

Recombinant human NQO-1 protein

ArtNr	NKM-ATGP0392-0.5mg
Hersteller	NKMAX
Menge	0.5mg
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	other
Konjugat/Tag	His-Tag
Purity	> 95% by SDS-PAGE
Sequence	Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MVGRRALIVL AHSERTSFNY AMKEAAAAAL KKKGWEVVES DLYAMNFNPI ISRKDITGKL KDPANFQYPA ESVLAYKEGH LSPDIVAEQK KLEAADLVIF QFPLQWFGVP AILKGWFERV FIGEFAYTYA AMYDKGPFRS KKAVLSITTG GSGSMYSLQG IHGDMNVILW PIQSGILHFC GFQVLEPQL
NCBI	NP_000894
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	NAD(P)H dehydrogenase quinone 1., DHQu, DIA4, DTD, NMOR1, NMORI, QR1, Azoreductase, Quinone reductase 1, DT-diaphorase, NAD(P)H dehydrogenase, quinone 1, Azoreductase.Menadione reductase, NQO 1, QR 1, Phylloquinone reductase, Cytochrome b 5 reductase, DIA 4, Diaphorase (NADH/NADPH), Diaphorase 4 Dioxin inducible 1, DT diaphorase, Diaphorase (NADH/NADPH) (cytochrome b 5 reductase), NAD(P)H dehydrogenase quinone 1 NAD(P)H menadione oxidoreductase 1 dioxin inducible, NAD(P)H: menadione oxidoreductase 1 dioxin inducible 1, NAD(P)H:menadione oxidoreductase 1, NAD(P)H:Quinone acceptor oxidoreductase type 1, NAD(P)H:quinone oxidoreductase 1, NAD(P)H:quinone oxireductase, NMOR 1, NMOR I.
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Antigen Species	Human
Applications info	SDS-PAGE
Concentration	1 mg/ml (determined by Bradford assay)
Description	NQO1 is a member of the NAD (P) H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This protein apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis. NQO1 functions as an important part of cellular antioxidant defense by detoxifying quinines thus preventing the formation of reactive oxygen species. Altered expression of NQO1 has been seen in many tumors and is also associated with Alzheimer's disease (AD). Recombinant NQO1 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Domain	1-274aa
Expression System	E.coli
Formulation	Liquid. In 20mM Tris-HCL buffer (pH 8.0) containing 10% glycerol 1mM DTT.
Gene Category	Redox Proteins
General References	Jaiswal AK., et al. (1988) J Biol Chem. 263(27):13572-8. Traver RD., et al. (1992) Cancer Res. 52(4):797-802.
Molecular Weight	33.0 kDa (294aa), confirmed by MALDI-TOF.
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

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Menge: 0.5mg

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Lieferung vsl. bis 30.08.2024

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