ArtNr |
NKM-ATGD0154-10ug |
Hersteller |
NKMAX
|
Menge |
10ug |
Kategorie |
|
Typ |
cDNA |
Specific against |
other |
Sequence |
ATGGAAGCTGTTGCCAAGTTTGATTTCACTGCTTCAGGTGAGGATGAACTGAGCTTTCACACTGGAGATGTTTTGAAGATTTTAAGTAACCAAGAGGAGTGGTTTAAGGCGGAGCTTGGGAGCCAGGAAGGATATGTGCCCAAGAATTTCATAGACATCCAGTTTCCCAAATGGTTTCACGAAGGCCTCTCTCGACACCAGGCAGAGAACTTACTCATGGGCAAGGAGGTTGGCTTCTTCATCATCCGGGCCAGC |
Vector |
pATGen (puc19 - derived cloning vector) |
NCBI |
NP_004801.1 |
ECLASS 10.1 |
32160414 |
ECLASS 11.0 |
32160414 |
UNSPSC |
41105324 |
Alias |
GADS, GRAP-2, GRB2L, GRBLG, GrbX, Grf40, GRID, GRPL, Mona, P38 |
Lieferbar |
|
Antigen Species |
Human |
Chromosome Location |
22q13.2 |
DNA size |
993bp |
Description |
GRAP2 encodes a member of the GRB2/Sem5/Drk family. GRAP2 member is an adaptor-like protein involved in leukocyte-specific protein-tyrosine kinase signaling. Like its related family member, GRB2-related adaptor protein (GRAP), GRAP2 contains an SH2 domain flanked by two SH3 domains. GRAP2 interacts with other proteins, such as GRB2-associated binding protein 1 (GAB1) and the SLP-76 leukocyte protein (LCP2), through its SH3 domains. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for GRAP2. |
Formulation |
Lyophilized |
Gene Category |
Cancer, Signal Transduction |
OMIM reference Number |
604518 |
Preparation before usage |
1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid. |
RNA Reference Number |
NM_004810.3 |
Storage |
Store the plasmid at -20C. |
Translation Sequence |
MEAVAKFDFT ASGEDELSFH TGDVLKILSN QEEWFKAELG SQEGYVPKNF IDIQFPKWFHEGLSRHQAEN LLMGKEVGFF IIRASQSSPG DFSISVRHED DVQHFKVMRD NKGNYFLWTEKFPSLNKLVD YYRTNSISRQ KQIFLRDRTR EDQGHRGNSL DRRSQGGPHL SGAVGEEIRPSMNRKLSDHP PTLPLQQHQH QPQPPQYAPA PQQLQQPPQQ RYLQHHHFHQ ERRGGSLDINDGHCGTGLGS EMNAALMHRR HTDPVQLQAA GRVRWARALY DFEALEDDEL GFHSGEVVEVLDSSNPSWWT GRLHNKLGLF PANYVAPMTR |
Vector description |
This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector. |
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