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Human PARP2 antibody

ArtNr NKM-ATGA0270-100ul
Hersteller NKMAX
Menge 100ul
Kategorie
Typ Antibody Monoclonal
Clon AT29G4
Specific against other
Host Mouse
Isotype IgG2a kappa
Konjugat/Tag Unconjugated
NCBI NP_005475
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Poly (ADP-ribose) polymerase 2, ADPRT2, ADPRTL2, ADPRTL3, ARTD2, pADPRT-2, PARP-2
Lieferbar
Antigen Species
Human
Applications info
ELISA, WB, FACS, ICC/IF
Clonality Mono VS Poly
Monoclonal
Concentration
1mg/ml
Description
PARP2 is poly (ADP-ribosyl) transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly (ADP-ribosyl) ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found.
Formulation
Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Gene Category
Epigenomics (Transcription & Translation)
General References
Ame JC, Rolli V, Schreiber V et al. (1999). J. Biol. Chem. 274 (25): 17860-8.
Schreiber V, Ame JC, Dolle P et al. (2002). J. Biol. Chem. 277 (25): 23028-36.
Maeda Y, Hunter TC, Loudy DE et al. (2006). J. Biol. Chem. 281 (14): 9600-6.
Immunogen
Recombinant human PARP2 (233-583aa) purified from E. coli
Reacts With
Human
Storage
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Usage
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ca. 1:5000. Recommended starting dilution is 1:500.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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