ArtNr |
NKM-ATGA0270-100ul |
Hersteller |
NKMAX
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Monoclonal |
Clon |
AT29G4 |
Specific against |
other |
Host |
Mouse |
Isotype |
IgG2a kappa |
Konjugat/Tag |
Unconjugated |
NCBI |
NP_005475 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Poly (ADP-ribose) polymerase 2, ADPRT2, ADPRTL2, ADPRTL3, ARTD2, pADPRT-2, PARP-2 |
Lieferbar |
|
Antigen Species |
Human |
Applications info |
ELISA, WB, FACS, ICC/IF |
Clonality Mono VS Poly |
Monoclonal |
Concentration |
1mg/ml |
Description |
PARP2 is poly (ADP-ribosyl) transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly (ADP-ribosyl) ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. |
Formulation |
Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. |
Gene Category |
Epigenomics (Transcription & Translation) |
General References |
Ame JC, Rolli V, Schreiber V et al. (1999). J. Biol. Chem. 274 (25): 17860-8. Schreiber V, Ame JC, Dolle P et al. (2002). J. Biol. Chem. 277 (25): 23028-36. Maeda Y, Hunter TC, Loudy DE et al. (2006). J. Biol. Chem. 281 (14): 9600-6. |
Immunogen |
Recombinant human PARP2 (233-583aa) purified from E. coli |
Reacts With |
Human |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Usage |
The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ca. 1:5000. Recommended starting dilution is 1:500. |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.