ArtNr |
NKM-ADJ0618-100ul |
Hersteller |
NKMAX
|
Menge |
100ul |
Kategorie |
|
Typ |
Antibody Monoclonal |
Clon |
1B11 |
Specific against |
other |
Host |
Mouse |
Isotype |
IgG1 kappa |
Konjugat/Tag |
Unconjugated |
NCBI |
NP_009193 |
ECLASS 10.1 |
42030590 |
ECLASS 11.0 |
42030590 |
UNSPSC |
12352203 |
Alias |
Parkinson disease protein 7, PARK7, DJ-1 (PARK7), Oncogene DJ1, Parkinson disease protein 7, Protein DJ-1, Parkinson disease protein 7 CAP1, DJ1, DJ1 protein, Oncogene DJ1, SP22. |
Lieferbar |
|
Antigen Species |
Human |
Applications info |
ELISA, WB (Cell lysate) |
Clonality Mono VS Poly |
Monoclonal |
Concentration |
1mg/ml |
Description |
Park7/DJ-1, which is a small 189 amino acid protein, is a ubiquitously expressed protein involved in various cellular processes including spermatogenesis and fertilization, cancer, RNA-binding, androgen-receptor signaling and oxidative stress. Mutations in the Park7/DJ-1 are the cause of autosomal recessive early-onset Parkinson's disease 7 (Park7). |
Formulation |
Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol. |
Gene Category |
Neuroscience |
General References |
Meulener MC. et al (2005) J. Neurochem. 93, 1524-1532 Bonifati V. et al (2003) Science. 299, 256-259 Zhou W. et al (2005) J. Biol. Chem. 280, 43150-43158 Junn E. et al (2005) PNAS. 102, 9691-9696 |
Immunogen |
Recombinant human Park7/DJ-1 (1-189 aa) purified from E. coli |
Reacts With |
Human |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Usage |
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ca. 2, 000. Recommended starting dilution is 1:1, 000. |
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