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Human BID antibody

Human BID antibody

ArtNr	NKM-ABI0923-50ul
Hersteller	NKMAX
Menge	50ul
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Clon	4D3
Specific against	other
Host	Mouse
Isotype	IgG1 kappa
Konjugat/Tag	Unconjugated
NCBI	NP_001187
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Alias	BH3 interacting domain death agonist isoform 2, FP497, MGC15319, MGC42355, BH3 interacting domain death agonist isoform 2, BID, BH3 interacting domain death agonist isoform 2 Apoptotic death agonist, Apoptotic death agonist BID, BH3 interacting domain death agonist, HGNC:1050, BH3 interacting domain death agonist p11, BH3 interacting domain death agonist p13, BH3 interacting domain death agonist p15, BID isoform ES(1b), BID isoform L(2), Desmocollin type 4, Human BID coding sequence, OTTHuMP00000196197, p11 BID, p13 BID, p15 BID, p22 BID.
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Antigen Species	Human
Applications info	ELISA, WB, ICC/IF
Clonality Mono VS Poly	Monoclonal
Concentration	1mg/ml
Description	BID is a pro-apoptotic Bcl-2 protein containing only the BH3 domain. In response to apoptotic signaling, BID interacts with another Bcl-2 family protein, Bax, leading to the insertion of Bax into the outer mitochondrial membrane. Bax is believed to induce the opening of the mitochondrial voltage-dependent anion channel. This results in the release of cytochrome c and other pro-apoptotic factors from the mitochondria leading to activation of caspases.
Formulation	Liquid. In Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol.
Gene Category	Apoptosis
General References	Zha J., et al. (2000) Science. 290:1761 Luo X., et al. (1998) Cell. 94:481 Li H., et al. (1998) Cell. 94:491
Immunogen	Recombinant human BID (1-195aa) purified from E. coli
Reacts With	Human
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Usage	The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:1, 000 ca. 2, 000. Recommended starting dilution is 1:1, 000.

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Menge: 50ul

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Lieferung vsl. bis 04.10.2024

Express-Lieferung: 32 Tage sparen

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