InvivoChem Cat #:V7131CAS #:524684-52-4Purity >=98%Description: Prinaberel, formerly known as ERB-041, is a biochemical which acts as a highly selective agonist of the ERbeta subtype of the estrogen receptor. It is used in scientific research to elucidate the role of the ERbeta receptor. Studies have indicated that selective ERbeta agonists like prinaberel could be useful in the clinical treatment of a variety of medical conditions including inflammatory bowel disease, rheumatoid arthritis, endometriosis, and sepsis. Accordingly, prinaberel either was or still is under investigation by Wyeth for the treatment of some of these conditions.
References: Hinsche O, Girgert R, Emons G, Gründker C. Estrogen receptor beta selective agonists reduce invasiveness of triple-negative breast cancer cells. Int J Oncol. 2015 Feb; 46(2):878-84. doi: 10.3892/ijo.2014.2778. Epub 2014 Nov 25. PubMed PMID: 25420519.