lofexidine-hcl

Description: Lofexidine (brand name Lucemyra among others), an analog of Clonidine, is a medication historically used to treat high blood pressure, but more commonly used to help with the physical symptoms of opioid withdrawal. It is an alpha2A adrenergic receptor agonist that has been approved for use by the Food and Drug Administration in the United States in 2018. The possibility of using lofexidine to treat alcohol withdrawal symptoms has been investigated, and has not yet been shown to be an effective treatment.5 It is also used in treatment of cases suffering from postmenopausal hot flashes.

References: J Addict Med. 2018 Nov 29. doi: 10.1097/ADM.0000000000000473; J Subst Abuse Treat. 2018 Aug; 91:1-11.

Related CAS#:31036-80-3 (free)