arformoterol

Description: Formoterol (also named as Arformoterol) is a long-acting beta2 agonist (LABA) used in the treatment of asthma and COPD (chronic obstructive pulmonary disease). It is marketed in three forms: a dry-powder inhaler, a metered-dose inhaler and an inhalation solution, under various trade names including Atock, Atimos/Atimos Modulite, Foradil/Foradile, Oxeze/Oxis, and Perforomist. It is also marketed in the combination formulations budesonide/formoterol and mometasone/formoterol. Formoterol has an extended duration of action (up to 12 h) compared to short-acting beta2 agonists such as salbutamol (albuterol), which are effective for 4 h to 6 h. LABAs such as formoterol are used as 'symptom controllers' to supplement prophylactic corticosteroid therapy. A 'reliever' short-acting beta2 agonist (e.g., salbutamol) is still required, since LABAs are not recommended for the treatment of acute asthma.

References: Am J Respir Cell Mol Biol. 2011 Jul; 45(1): 88–94; BMC Pediatr. 2012 Mar 7; 12:21.

Related CAS#:1254575-18-2 (maleate); 43229-80-7 (Formoterol fumarate); 67346-49-0 (free); 200815-49-2 (tartarate)