InvivoChem Cat #:V3656CAS #:2072057-17-9 Purity >=98%Description: RG7834 S-isomer, also known as RO 7020322 is the S-enantiomer of RG7834 (RO-7020322) which is a novel, potent and orally bioavailable inhibitor of HBV viral gene expression which blocks viral antigen and virion production. RG7834 is highly selective for HBV, and has a unique antiviral profile that is clearly differentiated from nucleos(t)ide analogues. RG7834 (also known as RO 7020322) is a novel, potent, highly selective and orally bioavailable HBV inhibitor which potently inhibits HBV antigens (both HBsAg and HBeAg) and HBV DNA, with IC50s of 2.8, 2.6, and 3.2 nM, respectively in dHepaRG Cells. RG7834 is a novel oral HBV viral gene expression inhibitor that blocks viral antigen and virion production. RG7834 has a unique antiviral profile that is clearly differentiated from nucleos(t)ide analogues.
References: J Med Chem. 2018 Oct 4.
Related CAS#: 2072057-17-9 (S-isomer); 2072057-18-0 (R-isomer); 199482-36-3 (S-isomer hydrate); 1802407-46-0 (racemic)