InvivoChem Cat #:V3363CAS #:112924-45-5 Purity >=98%Description: HU-211 (Dexanabinol) is a novel, potent synthetic terpene-based cannabinoid devoid of central cannabinoid (CB1) and peripheral cannabinoid (CB2) agonist activity, thus lacking the psychomotor responses characteristic of delta9-THC. HU-211 does exhibit the neuroprotective, antioxidant properties of other related compounds like cannabidiol. HU-211 also has anti-inflammatory properties derived through inhibition of NF-kappaB and the resulting decreases in cytokines such as TNFalpha and interleukin-6. The endocannabinoids present a rich system of central cannabinoid (CB1), peripheral cannabinoid (CB2), and non-CB receptor-mediated pharmacology that has stimulated research in many fields including memory, weight loss and appetite, neurodegeneration, tumor surveillance, analgesia, and inflammation.
Description:References: Neuropharmacology 47, 580-592 (2004).
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