rivastigmine

Description: Rivastigmine, also known as ENA-713 and SDZ-ENA 713, is a reversible cholinesterase inhibitor with IC50 of 5.5 uM, it is used as a parasympathomimetic or cholinergic agent for the management of mild to moderate Alzheimer disease, Dementia, and Parkinson's Disease. Rivastigmine is a carbamate-derived reversible cholinesterase inhibitor that is selective for the central nervous system . It acts by covalently modifying a serine residue in the active site by carbamoylation, as it stabilizes or reduces the rate of decline in certain cognitive functions.

References: J Clin Neurol. 2011 Sep; 7(3):137-42.

Related CAS: 194930-00-2 (R)-Rivastigmine D6 tartrate