InvivoChem Cat #:V26003CAS #:367909-40-8Purity >=98%Description: MRS2279 is a potent, selective and competitive antagonist of the P2Y1 receptor with a Ki of 2.5 nM and an IC50 of 51.6 nM. MRS2279 potently inhibits ADP-induced aggregation of human blood platelets in vitro (pKB = 8.05).
References: Khan S, Yan-Do R, Duong E, Wu X, Bautista A, Cheley S, MacDonald PE, Braun M. Autocrine activation of P2Y1 receptors couples Ca (2+) influx to Ca (2+) release in human pancreatic beta cells. Diabetologia. 2014 Dec; 57(12):2535-45. doi: 10.1007/s00125-014-3368-8.