Davercin (Erythromycin cyclocarbonate)

Description: Davercin (Erythromycin cyclocarbonate), an Erythromycin derivative, is a potent bacteriostatic antibiotic macrolide produced by Streptomyces erythreus and is active against Gram-positive and some Gram-negative microorganisms. It inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.

References: From Erythromycin to Azithromycin and New Potential Ribosome-Binding Antimicrobials. Antibiotics (Basel). 2016 Sep 1; 5(3). pii: E29; Isolation and characterization of a high-efficiency erythromycin A-degrading Ochrobactrum sp. strain. Mar Pollut Bull. 2017 Jan 30; 114(2):896-902. doi: 10.1016/j.marpolbul.2016.10.076. PubMed PMID: 27863881.

Related CAS: 114-07-8 (free); 3521-62-8 (estolate); 16667-03-1 (glutamate); 30010-41-4 (aspartate); 7704-67-8 (thiocyante); 1264-62-6 (Ethylsuccinate); 914076-30-5 (ethyl carbonate); 55224-05-0 (cyclocarbonate); 33396-29-1 (Erythromycin A enol ether); 59319-72-1 (Erythromycin A dihydrate)